Saturday 2 July 2016
Human organs grown in pigs may help transplant patients, scientists say
Researchers are in the very early stages
of using adult stem cells to grow human organs. The twist: These human
organs are being grown inside animals.
Every day, about 22 people in the United States die while waiting for organ transplants, according to federal statistics.
In
an attempt to solve the global donor-organ shortage, researchers at the
University of California, Davis have created embryos that have both
human and pig cells.
These cells are created by taking human stem cells from an adult's skin or hair, using them in a pig embryo and injecting it into the uterus of a pig.
The
embryo needs a few weeks to mature for scientists to determine whether
the procedure worked, but after 28 days, the pigs' pregnancies were
terminated, and the cell remnants were analyzed.
Besides
growing organs for transplant patients, this technology may help treat
people with life-threatening diseases like diabetes, said scientist Juan
Carlos Izpisua Belmonte of the Salk Institute for Biological Studies in La Jolla, California.
Belmonte is working with UC-Davis' Pablo Ross on this research. Their work is being funded in part by the Defense Department and the California Institute for Regenerative Medicine.
Getting
to the point of creating human-animal hybrid organs is possible because
of the combination of two breakthrough techniques in stem cell biology
and gene-editing technology.
Scientists
are able to knock out a section of an animal's DNA, such as the
pancreas, so a pig embryo won't have the information it needs to make
that particular organ.
Then, stem
cells come into play. Once injected into the embryo, the adult stem
cells will start working on creating a pancreas. Since embryos don't
have immune systems, they can't reject the foreign cells.
The
next step, which Belmonte said is still a dream, is that old, damaged
or sick human organs could be easily replaced, possibly saving thousands
of lives each year.
When man and beast unite
What makes stem cells so special is that they can form any type of tissue.
The
stem cells are injected into an embryo at such an early stage, when the
embryo is just a few cells in a Petri dish, that they can essentially
develop into any part of of an animal's body.
That possibility also makes the research controversial.
The
mix of human and animal DNA in modern medicine is known as chimera. The
name is inspired by a monstrous creature from Greek mythology that is
depicted as part lion, part goat and part snake.
The U.S. National Institutes of Health
announced in November that it would not support this human-animal
research after reviewing a presentation from scientists working in the
field.
The institutes' main concern
involves the concept of chimeras acquiring a cognitive state.
Scientists are essentially asking themselves what happens if human stem
cells somehow start to create a human brain inside an animal.
It's a major bioethical question, according to Paul Root Wolpe, director of the Center of Ethics at Emory University.
"If
you were creating a pig with a heart made from human cells, is that OK?
I think it is. There's nothing magical about the human cell," Wolpe
said.
But the landscape gets
murkier if there's a possibility of an animal experiencing human
thoughts, Wolpe explained. Mental cognition is an intrinsically human
experience.
"This is pretty crude
procedure. We are throwing stem cells into embryonic cells and hoping
that it works out. We have to be really careful about that," he said.
Although
the risk of an animal acquiring human consciousness is slim -- their
brains are smaller than and different from humans' -- anything is
possible, Belmonte said.
"We need
to consider all the possibilities. Where the cells go is a major
question. They can go to the brain or anywhere," he said.
But the National Institutes of Health's funding ban has drawn criticism
from scientists, including Daniel Garry, a cardiologist who leads a
chimera project at the University of Minnesota, who said the agency's
stance is inhibiting medical progress and creating a stigma around the
research.
'Personalizing' the future of medicine
Other
than transforming to essentially anything, human stem cells are
important in chimera research because they can limit the chance of a
human-pig organ being rejected by a transplant patient's body.
"With the compatibility of these cells, this will open the door for personalizing medicine," Belmonte said.
So why grow organs inside a pig, anyway?
The creature's organs are almost the same size as ours, said Walter Low, professor at the University of Minnesota's Department of Neurosurgery.
"The
animal is acting as a biological incubator," Low said. "If the stem
cells were taken from a patient with diabetes, those stem cells are
identical to the patient's own cells."
Low has been using stem cells to treat neurological disorders such as Parkinson's disease, a condition that affects the central nervous system.
This
idea of chimera organs isn't a new concept, Low explained. In 2010,
Japanese scientist Hiromitsu Nakauchi, who is now a stem cell biologist
at Stanford University, was able to grow a rat pancreas inside a mouse.
This was a huge breakthrough in chimera research because rats and mice
are different species.
Saturday 25 June 2016
Russia aim to make Star Trek-style teleportation a reality within 20 years
Russia aim to make Star Trek-style teleportation a reality within 20 years
If you have been a avid Star Trek follower you may have seen Captain Kirk and Spock beam themselves upto to some different planet as a click of a button. The legendary dialogue by Captain Kirk, ‘Beam Me Up Scotty‘ looks to be reality soon. Russia is embarking on a ambitious Star Trek style teleporatation program and its research program has received financial backing from the Russian government. The program seems to be part of a new Kremlin drive to encourage Russia’s IT sector and high-tech economy.A proposed multi-trillion pound strategic development program drawn up for Vladimir Putin would seek to develop teleportation by 2035. According to Kommersant, the $2.1 trillion (£1.4 trillion) “road map” for development of the cybernetics market to 2035 also includes developing a Russian computer programming language, secure cybernetic communications, quantum computing, and neural interfaces (direct connections between computers and human brains).
“It sounds fantastical today, but there have been successful experiments at Stanford at the molecular level,” Alexander Galitsky, a prominent investor in the country’s technology sector, told Russia’s Kommersant daily on Wednesday. “Much of the tech we have today was drawn from science fiction films 20 years ago.”
However, the goal is not as far-fetched as it may sound.
“It is important to have intermediate goals to have an opportunity to correct the road map and its realization in order not to get involved in knowingly utopian spheres,” he said.
For the first time in 2014, scientists at Delft University of Technology in the Netherlands presented that it was possible to teleport information programmed into sub-atomic particles between two points three metres apart with 100% dependability.
Even though teleportation remains a remote prospect, experts believe that the next few decades will likely see significant progress in quantum computing and neural interfaces.
Earlier this week, Mr Putin showered praise on Russia’s IT sector when he met a team of programmers from St. Petersburg State University who won the 2016 international “Programming Olympiad.”
Russia not only has a talented programming community but also a small and lively software sector that has created many successful IT companies, including Kaspersky Labs and Yandex.
Western governments are also of the opinion that Russia has leveraged its computing talent to make one of the most impressive state-sponsored hacking and cyber-warfare programs in the world.
Meet the guy who refused to sell Kanyeforpresident.com for $80,000
This guy refused a whoppping $80,000 offer to sell kanyeforpresident.com to Kanye West
You may already know Kanye West who has been making more news off the stage than on it. West who is also married to one the top celebrities of Hollywood, Kim Kardashian managed to deliver one hit album, The Life of Pablo.However West has other dreams also. He wants to be the President of the United States of America
When you visit kanyeforpresident website, you will be taken to the Instagram page of Tramall Ferguson.
“I was just trying to do something out of the box,” Tramall told ABC’s Control Z podcast.
He then made two impulse purchases: kanyeforpresident.com and petergriffinforpresident.com.
“I thought it was clever and no one had it yet, so I went ahead and did it,” Tramall says, “And then I literally forgot that I had it.”
“I got a call from some guy, he was offering me like, $30,000 at first. And I didn’t even know that he was offering me money for it, so I was just like, ‘50 grand!’ And he was like, ‘35’, and I was like, ‘50!’ and he was like, I’ll call you back.
“Then I got a call from Greg at TMZ, and then that’s when I kind of raised my eyebrows.
“Then I started getting crazy phone calls that day with people throwing out offers. The highest one on the first day was about 80 grand.
“[It was] like getting a lottery ticket and just winning. That’s basically what happened,” Tramall says.
Domain names can be a good business if you know how to deal in websites. Otherwise you have to plain lucky like Tramall above or Sanmay Ved who purchased Google.com for $10 during a night surfing expedition. Like Tramall, Sanmay too would have made millions from his buy but he chose to give back the domain to Google for something like $10,000 to be donated to charity.
Forget Electronic Hard Drives, Now Bacteria Can Store Information
We can use bacteria as living hard drives to store vast amounts of information state scientists
Instead of those bulky hard drives, soon we would be storing vast amounts of information on a bacteria. Yes, the humble bacteria can store information just like hard drives say scientists.Harvard scientists led by Jeff Nivala and Seth Shipman have discovered a remarkable way to store lines of code in living bacteria, which can then be passed down to the next generation as genetic information. Based on a new study, bacteria colonies when fed by a series of human-written data can transform tiny cells into living hard drives.
According to Shipman, genotyping the bacteria could easily read the data from these living memory sticks. This type of experiment allows the transfer of 100 bytes of data, almost ten times more than possible with artificial DNA. Previously, the scientists had attempted this experiment but with synthetic DNA. The technique used by the scientists practically tricked the bacteria into copying actual computer code into their DNA without compromising their own cellular activities.
“We write the information directly into the genome. While the overall amount of DNA data we have currently stored within a genome is relatively small compared to the completely synthetic DNA data storage systems, we think genome-based information storage has many potential advantages,” Nivala told Gizmodo. He says that these advantages could include higher fidelity and the capability to directly interface with biology. For example, a bacterium could be taught to identify, provide information, and even kill other microorganisms in its midst, or provide a record of genetic expression.
Going forward, the kind of bacteria one uses is important. The researchers used E. coli for this particular experiment that clocks in a fairly respectable storage of 100 bytes. However, certain bacteria, such as Sulfolobus tokodaii may be capable of storing thousands of bytes.
To protect certain bacteria from viral infection, the scientists used the bacteria’s built-in immune system called CRISPR or Cas system. When the bacteria are attacked by viruses, they physically cut out a segment of the invaders’ DNA and paste it into a specific region of their own genome. This way, if that same virus attacks again, the bacteria can identify it and respond accordingly. Thus, the cell passes this information over to its progeny of the bacteria, transferring the viral immunity to next generations.
The bacteria research team discovered that by introducing a segment of genetic data that looks like viral DNA into a colony of bacteria that have the CRISPR/Cas system, the bacteria would devour it and include it in their genetic code. Therefore, the scientists spread the loose segments of DNA into the E.coli bacterial colony that had the CRISPR. They gulped it all up essentially becoming tiny, living hard drives.
Conveniently enough, the bacteria store new immune system entries in sequence, with earlier viral DNA recorded before that of more recent infections.
“That’s quite important,” Shipman says. “If the new information was just stored randomly, that wouldn’t be nearly as informative. You’d have to have tags on each piece of information to know when it was introduced into the cell. Here it’s ordered sequentially, like the way you write down the words in a sentence.”
Wednesday 18 May 2016
LINKIN PARK LYRICS
Yeah here we go for the hundredth time
Hand grenade pins in every line
Throw 'em up and let something shine
Going out of my fucking mind
Filthy mouth, no excuse
Find a new place to hang this noose
String me up from atop these roofs
Knot it tight so I won't get loose
Truth is you can stop and stare
Bled myself out and no one cares
Dug the trench out laid down there
With a shovel up out of reach somewhere
Yeah, someone pour it in
Make it a dirt dance floor again
Say your prayers and stomp it out
When they bring that chorus in
[Chorus]
I bleed it out digging deeper
Just to throw it away
I bleed it out digging deeper
Just to throw it away
I bleed it out digging deeper
Just to throw it away
Just to throw it away
Just to throw it away
I bleed it out
Go stop the show
Choppy words and a sloppy flow
Shotgun opera lock and load
Cock it back and then watch it go
Mama help me I've been cursed
Death is rolling in every verse
Candy paint on his brand new hearse
Can't contain him he knows he works
Fuck this hurts, I won't lie
Doesn't matter how hard I try
Half the words don't mean a thing
And I know that I won't be satisfied
So why try ignoring him?
Make it a dirt dance floor again
Say your prayers and stomp it out
When they bring that chorus in
[Chorus]
I bleed it out digging deeper
Just to throw it away
I bleed it out digging deeper
Just to throw it away
I bleed it out digging deeper
Just to throw it away
Just to throw it away
Just to throw it away
I bleed it out
I've opened up these scars
I'll make you face this
I've pulled myself so far
I'll make you face this now!
[Chorus]
I bleed it out digging deeper
Just to throw it away
I bleed it out digging deeper
Just to throw it away
I bleed it out digging deeper
Just to throw it away
Just to throw it away
Just to throw it away
I bleed it out digging deeper
Just to throw it away
I bleed it out digging deeper
Just to throw it away
I bleed it out digging deeper
Just to throw it away
Just to throw it away
Just to throw it away
I bleed it out
I bleed it out
I bleed it out
Hand grenade pins in every line
Throw 'em up and let something shine
Going out of my fucking mind
Filthy mouth, no excuse
Find a new place to hang this noose
String me up from atop these roofs
Knot it tight so I won't get loose
Truth is you can stop and stare
Bled myself out and no one cares
Dug the trench out laid down there
With a shovel up out of reach somewhere
Yeah, someone pour it in
Make it a dirt dance floor again
Say your prayers and stomp it out
When they bring that chorus in
[Chorus]
I bleed it out digging deeper
Just to throw it away
I bleed it out digging deeper
Just to throw it away
I bleed it out digging deeper
Just to throw it away
Just to throw it away
Just to throw it away
I bleed it out
Go stop the show
Choppy words and a sloppy flow
Shotgun opera lock and load
Cock it back and then watch it go
Mama help me I've been cursed
Death is rolling in every verse
Candy paint on his brand new hearse
Can't contain him he knows he works
Fuck this hurts, I won't lie
Doesn't matter how hard I try
Half the words don't mean a thing
And I know that I won't be satisfied
So why try ignoring him?
Make it a dirt dance floor again
Say your prayers and stomp it out
When they bring that chorus in
[Chorus]
I bleed it out digging deeper
Just to throw it away
I bleed it out digging deeper
Just to throw it away
I bleed it out digging deeper
Just to throw it away
Just to throw it away
Just to throw it away
I bleed it out
I've opened up these scars
I'll make you face this
I've pulled myself so far
I'll make you face this now!
[Chorus]
I bleed it out digging deeper
Just to throw it away
I bleed it out digging deeper
Just to throw it away
I bleed it out digging deeper
Just to throw it away
Just to throw it away
Just to throw it away
I bleed it out digging deeper
Just to throw it away
I bleed it out digging deeper
Just to throw it away
I bleed it out digging deeper
Just to throw it away
Just to throw it away
Just to throw it away
I bleed it out
I bleed it out
I bleed it out
Friday 6 May 2016
Low Latent Inhibition What exactly is Low Latent Inhibition?
Latent inhibition
In order to even attempt to explain what low latent inhibition is, I feel it is vital that an understanding of the term “latent inhibition” is reached. Latent inhibition is a term used to explain how our observation of a familiar stimulus (e.g. something we see, hear, smell, feel or taste that we’ve had before) takes longer to acquire meaning than a new stimulus. It’s essentially a mental tool you develop in order to experience the world in a manageable way. You use latent inhibition in your day-to-day interactions with the environment.
For example, consider how you experience a doorknob. You are familiar with door handles and how they work, what the purpose of them is and in most cases a door handle wouldn’t interest you enough for you to pay it any notice. Why should you? You know how they work already and have seen them before. Your brain applies the same rule to different types of door handles on all sorts of doors, “It is there so that I can open this door”. You do not question the choice of door handles or look into the finer details in terms of why that door handle in particular was chosen, because if your brain had to do this every time a new stimulus presented itself it wouldn’t be able to cope and would overload. This is why we have Latent Inhibition. It allows us to distinguish familiar doorknobs from unfamiliar doorknobs so we can simplify how we experience the world.
Low latent inhibition
With low latent inhibition, an individual almost treats familiar stimuli in the same manner as they would new stimuli. Think of the details you notice when you see something new for the first time and how it grabs your attention. From those details all kinds of questions may arise in your mind. “What is that, what does it do, why is it there, what does it mean, how can it be utilized” and so on. The more of those questions you are able to figure out or answer, the better your understanding of that stimulus. The better your understanding of that stimulus, the more logical connections you are able to make between that stimulus and others around it. With the use of human memory you are then able to remember which questions you’ve already answered in relation to a particular stimulus, and those answers may then result in more questions. Low latent inhibition will usually result in extremely accurate instincts due to the sheer level of thought, processing and logical connection that has been made previously when faced with a stimulus or multiple stimuli.
So in terms of what we might see, somebody you know who’s generally always worn glasses might approach you having bought a new pair of glasses that look almost exactly the same but for a slightly different logo on the side. You usually wouldn’t notice the change of logo because your brain has almost dismissed the minor details that go with the pair of glasses they wear as ‘unimportant’. It’s your brains way of ensuring that it doesn’t need to constantly process new stimuli that probably won’t have any significance or importance to it. Yes they might wear glasses, but so what? In this example we simply see the glasses then move on.
An example of how somebody with low latent inhibition may see the same scenario could be that they almost instantly notice the smallest changes that seeing the new pair of glasses presents to them via the observation of stimuli, which may then lead to connections being made that people with normal latent inhibition might not make. For example from seeing the new logo, somebody with a low latent inhibition might deduce that their friend had been shopping since the last time they saw them, if they had been shopping they might have also recently received their monthly salary which meant they were able to buy the glasses. Did the friend have some insecurity with the last pair of glasses? If the person with low latent inhibition also knows the surrounding area well (and knows where the stores are that sell new glasses), and they know when the last time they saw their friend wearing his old glasses was (2 days ago), they might be able to work out the exact locations their friend will have been to, and depending upon which food their friend likes, where their friend might have eaten, and depending upon what their friends interests are, which other stores they might have been to after having been paid and what kind of things they might have bought…all from a small change of logo on a pair of glasses.
That same process can be true when any form of stimulus is observed by someone with low latent inhibition, and can be particularly effective in everyday use with regards to problem solving, data analysis, creativity, artistic expression and an infinite number of other possibilities. How do you think somebody with low latent inhibition and a high IQ (so that their brain can handle the constant influx of stimuli), might fare if stranded in a forest for example, miles away from anybody else and with no tools or no help readily available? The low latent inhibition would allow them to not only process and understand all stimuli in their surrounding environment, but to utilize that stimuli to further their goal and to help them adapt.
A great example of how a lot of people work with LLI is their brains naturally work on a “why, why, why, why” basis until they get to the root cause or origins of anything, rules, thoughts, someones intentions, someones actions, machinery etc. An example could be that most people when asked “why do you clean your teeth”, would answer “because i want them to be clean”, “Why”, “because I’m hygienic and i want them to look nice”, “why”, “because if they look nice other people will notice and i want that”, “why”, “because i want to look attractive to other people”, “why”, “so that i can find a partner i guess”. THERE is the root cause, they want to find a partner. People with LLI (at least like my own LLI) are always automatically asking and answering those why questions based on our intuition and perception, and because the intuition and perception of a few with LLI are based on far more stimuli (and therefore details noticed) they are extremely accurate. So in the above example if someone with LLI was asked why they think someone cleans their teeth – their intuition and perception going by the person in front of them would usually instantly result in an answer of “because they want to seem physically more appealing to a potential mate” (we would not starve to death if we lost all our teeth in this day and age). Their brain will have already asked and answered many WHY WHY WHY WHY WHY questions. That same automatic process applies to almost everything someone with LLI comes into contact with.
Further Details
Almost all those who have low latent inhibition are unaware that they are experiencing the world in a totally unique and different way compared to other people. It is generally only through interaction with people who don’t have low latent inhibition and the reactions of those people that brings about the feeling of being ‘unexplainably different’. People may for example laugh at your ideas or the connections that you are able to make or ridicule them (due to lack of understanding on their part), or may look at you as being extremely arrogant or a ‘know it all’. This is because extremely advanced logical connections made by someone with low latent inhibition will often feel like common sense, when in reality those without low latent inhibition wouldn’t even have considered those connections as a possibility. It can also mean that you come across as very intolerant at times (because perfectly reasonable suggestions by people without LLI might just seem stupid to you). There are many different characteristics than can be attributed to the condition; you will find some on the “advantages and disadvantages page” and many, many more on the Facebook awareness group and our forum.
Although low latent inhibition can be an incredible gift it does require a high enough IQ in order for your brain to handle the constant processing of stimuli. Without a sufficient IQ level, having low latent inhibition may lead to various forms of autism. It should also be noted that most autistic people have a lower than normal level of latent inhibition, which is one of the many reasons it is so difficult to confirm an LLI diagnosis. We believe that a lot of cases of LLI are actually missed or misdiagnosed as OCD, ADHD or Asperger’s syndrome but to name a few.
Do I have low latent inhibition?
It is incredibly hard to self-diagnose and we are finding that it is much easier for people to reach a successful diagnosis by meeting others with LLI. There is an exceptionally unique sense of relief when you meet other people who are ‘exactly like you’, your whole perspective on life and living with low latent inhibition will change and hopefully become more comfortable. For those out there with LLI, chances are that most of the difficulties you have faced or have yet to face have been experienced by others with the condition too. A lot of the relief we have witnessed by people who come to the Facebook group stems from knowing why they have felt different, that they are not alone and that there are others like them who are there to help.
We also believe that it is important to acknowledge that there are probably thousands of people if not more who have a lower than usual latent inhibition and that it’s not as rare as people may think. The very rare side to LLI is possessing true creative genius, or not suffering from autism as well as having LLI. Almost all autistic people may indeed have LLI, but that doesn’t mean their brains can handle having it, or that they can utilise it to its full effect. It’s extremely rare to have LLI and be able to use it in the incredibly unique ways in which its benefits can be used throughout life. It’s even more unlikely to have high IQ (over 130), and LLI, no autism and have manageable anxiety levels.
We would also like to stress that LLI is not one specific trait or characteristic and that it’s different in every case. Many might have a lower than usual latent inhibition but in such a way that they don’t feel many benefits and aren’t creating any masterpieces or aren’t extremely gifted in several areas. It is important to not panic or feel down if you think you have LLI but that it’s not making you a genius or that it only seems to give you trouble, as that is far more usual than having LLI and being classed as a genius. To use an example easier to follow, if LLI is chicken in terms of food recipes, ADHD might be salsa, OCD might be barbecue sauce, Asperger’s syndrome might be salad, and your IQ level might be the seasoning. There are obviously many other combinations or other ‘recipes’ you could make, but only a rare few would achieve the ultimate true taste that you’d want.
There are currently no official diagnostic tests for low latent inhibition, and no scale in terms of just how low ones latent inhibition might be. Both of those are things that we are currently working to address and we will be publishing our finds as we continue to delve into the area. We are also researching the work of Carl Jung, Katharine C Briggs and Isabel Briggs Myers with regards to personality types, as we wish look into just how different personality types can characterise low latent inhibition.
There are many different interpretations of low latent inhibition out there; some written by those who don’t have it themselves, some copied from an original source and pasted throughout the internet and some that we and I myself cannot relate to. I decided to write the above in an effort to reach as wide an audience as possible and to try and clarify exactly what LLI is. Here on the resource and discovery centre you will come across several different descriptions of low latent inhibition, all given by people who live with it and have spent years trying to understand and manage it.
In order to even attempt to explain what low latent inhibition is, I feel it is vital that an understanding of the term “latent inhibition” is reached. Latent inhibition is a term used to explain how our observation of a familiar stimulus (e.g. something we see, hear, smell, feel or taste that we’ve had before) takes longer to acquire meaning than a new stimulus. It’s essentially a mental tool you develop in order to experience the world in a manageable way. You use latent inhibition in your day-to-day interactions with the environment.
For example, consider how you experience a doorknob. You are familiar with door handles and how they work, what the purpose of them is and in most cases a door handle wouldn’t interest you enough for you to pay it any notice. Why should you? You know how they work already and have seen them before. Your brain applies the same rule to different types of door handles on all sorts of doors, “It is there so that I can open this door”. You do not question the choice of door handles or look into the finer details in terms of why that door handle in particular was chosen, because if your brain had to do this every time a new stimulus presented itself it wouldn’t be able to cope and would overload. This is why we have Latent Inhibition. It allows us to distinguish familiar doorknobs from unfamiliar doorknobs so we can simplify how we experience the world.
Low latent inhibition
With low latent inhibition, an individual almost treats familiar stimuli in the same manner as they would new stimuli. Think of the details you notice when you see something new for the first time and how it grabs your attention. From those details all kinds of questions may arise in your mind. “What is that, what does it do, why is it there, what does it mean, how can it be utilized” and so on. The more of those questions you are able to figure out or answer, the better your understanding of that stimulus. The better your understanding of that stimulus, the more logical connections you are able to make between that stimulus and others around it. With the use of human memory you are then able to remember which questions you’ve already answered in relation to a particular stimulus, and those answers may then result in more questions. Low latent inhibition will usually result in extremely accurate instincts due to the sheer level of thought, processing and logical connection that has been made previously when faced with a stimulus or multiple stimuli.
So in terms of what we might see, somebody you know who’s generally always worn glasses might approach you having bought a new pair of glasses that look almost exactly the same but for a slightly different logo on the side. You usually wouldn’t notice the change of logo because your brain has almost dismissed the minor details that go with the pair of glasses they wear as ‘unimportant’. It’s your brains way of ensuring that it doesn’t need to constantly process new stimuli that probably won’t have any significance or importance to it. Yes they might wear glasses, but so what? In this example we simply see the glasses then move on.
An example of how somebody with low latent inhibition may see the same scenario could be that they almost instantly notice the smallest changes that seeing the new pair of glasses presents to them via the observation of stimuli, which may then lead to connections being made that people with normal latent inhibition might not make. For example from seeing the new logo, somebody with a low latent inhibition might deduce that their friend had been shopping since the last time they saw them, if they had been shopping they might have also recently received their monthly salary which meant they were able to buy the glasses. Did the friend have some insecurity with the last pair of glasses? If the person with low latent inhibition also knows the surrounding area well (and knows where the stores are that sell new glasses), and they know when the last time they saw their friend wearing his old glasses was (2 days ago), they might be able to work out the exact locations their friend will have been to, and depending upon which food their friend likes, where their friend might have eaten, and depending upon what their friends interests are, which other stores they might have been to after having been paid and what kind of things they might have bought…all from a small change of logo on a pair of glasses.
That same process can be true when any form of stimulus is observed by someone with low latent inhibition, and can be particularly effective in everyday use with regards to problem solving, data analysis, creativity, artistic expression and an infinite number of other possibilities. How do you think somebody with low latent inhibition and a high IQ (so that their brain can handle the constant influx of stimuli), might fare if stranded in a forest for example, miles away from anybody else and with no tools or no help readily available? The low latent inhibition would allow them to not only process and understand all stimuli in their surrounding environment, but to utilize that stimuli to further their goal and to help them adapt.
A great example of how a lot of people work with LLI is their brains naturally work on a “why, why, why, why” basis until they get to the root cause or origins of anything, rules, thoughts, someones intentions, someones actions, machinery etc. An example could be that most people when asked “why do you clean your teeth”, would answer “because i want them to be clean”, “Why”, “because I’m hygienic and i want them to look nice”, “why”, “because if they look nice other people will notice and i want that”, “why”, “because i want to look attractive to other people”, “why”, “so that i can find a partner i guess”. THERE is the root cause, they want to find a partner. People with LLI (at least like my own LLI) are always automatically asking and answering those why questions based on our intuition and perception, and because the intuition and perception of a few with LLI are based on far more stimuli (and therefore details noticed) they are extremely accurate. So in the above example if someone with LLI was asked why they think someone cleans their teeth – their intuition and perception going by the person in front of them would usually instantly result in an answer of “because they want to seem physically more appealing to a potential mate” (we would not starve to death if we lost all our teeth in this day and age). Their brain will have already asked and answered many WHY WHY WHY WHY WHY questions. That same automatic process applies to almost everything someone with LLI comes into contact with.
Further Details
Almost all those who have low latent inhibition are unaware that they are experiencing the world in a totally unique and different way compared to other people. It is generally only through interaction with people who don’t have low latent inhibition and the reactions of those people that brings about the feeling of being ‘unexplainably different’. People may for example laugh at your ideas or the connections that you are able to make or ridicule them (due to lack of understanding on their part), or may look at you as being extremely arrogant or a ‘know it all’. This is because extremely advanced logical connections made by someone with low latent inhibition will often feel like common sense, when in reality those without low latent inhibition wouldn’t even have considered those connections as a possibility. It can also mean that you come across as very intolerant at times (because perfectly reasonable suggestions by people without LLI might just seem stupid to you). There are many different characteristics than can be attributed to the condition; you will find some on the “advantages and disadvantages page” and many, many more on the Facebook awareness group and our forum.
Although low latent inhibition can be an incredible gift it does require a high enough IQ in order for your brain to handle the constant processing of stimuli. Without a sufficient IQ level, having low latent inhibition may lead to various forms of autism. It should also be noted that most autistic people have a lower than normal level of latent inhibition, which is one of the many reasons it is so difficult to confirm an LLI diagnosis. We believe that a lot of cases of LLI are actually missed or misdiagnosed as OCD, ADHD or Asperger’s syndrome but to name a few.
Do I have low latent inhibition?
It is incredibly hard to self-diagnose and we are finding that it is much easier for people to reach a successful diagnosis by meeting others with LLI. There is an exceptionally unique sense of relief when you meet other people who are ‘exactly like you’, your whole perspective on life and living with low latent inhibition will change and hopefully become more comfortable. For those out there with LLI, chances are that most of the difficulties you have faced or have yet to face have been experienced by others with the condition too. A lot of the relief we have witnessed by people who come to the Facebook group stems from knowing why they have felt different, that they are not alone and that there are others like them who are there to help.
We also believe that it is important to acknowledge that there are probably thousands of people if not more who have a lower than usual latent inhibition and that it’s not as rare as people may think. The very rare side to LLI is possessing true creative genius, or not suffering from autism as well as having LLI. Almost all autistic people may indeed have LLI, but that doesn’t mean their brains can handle having it, or that they can utilise it to its full effect. It’s extremely rare to have LLI and be able to use it in the incredibly unique ways in which its benefits can be used throughout life. It’s even more unlikely to have high IQ (over 130), and LLI, no autism and have manageable anxiety levels.
We would also like to stress that LLI is not one specific trait or characteristic and that it’s different in every case. Many might have a lower than usual latent inhibition but in such a way that they don’t feel many benefits and aren’t creating any masterpieces or aren’t extremely gifted in several areas. It is important to not panic or feel down if you think you have LLI but that it’s not making you a genius or that it only seems to give you trouble, as that is far more usual than having LLI and being classed as a genius. To use an example easier to follow, if LLI is chicken in terms of food recipes, ADHD might be salsa, OCD might be barbecue sauce, Asperger’s syndrome might be salad, and your IQ level might be the seasoning. There are obviously many other combinations or other ‘recipes’ you could make, but only a rare few would achieve the ultimate true taste that you’d want.
There are currently no official diagnostic tests for low latent inhibition, and no scale in terms of just how low ones latent inhibition might be. Both of those are things that we are currently working to address and we will be publishing our finds as we continue to delve into the area. We are also researching the work of Carl Jung, Katharine C Briggs and Isabel Briggs Myers with regards to personality types, as we wish look into just how different personality types can characterise low latent inhibition.
There are many different interpretations of low latent inhibition out there; some written by those who don’t have it themselves, some copied from an original source and pasted throughout the internet and some that we and I myself cannot relate to. I decided to write the above in an effort to reach as wide an audience as possible and to try and clarify exactly what LLI is. Here on the resource and discovery centre you will come across several different descriptions of low latent inhibition, all given by people who live with it and have spent years trying to understand and manage it.
Thursday 28 April 2016
4 Undie Styles Everyone Should Have
If your underwear drawer only consists of your one favorite style (or
you've just never put too much thought into what styles and fabrics
fill up your panty collection), try checking out all the different underwear pieces you should own,
according to the experts. That's right — I've sourced four specific
categories of underwear (divvied up by the different activities you do
while wearing them), and come up with 12 awesome styles to fit anyone's
preference.
If you're a loungewear lover, it's time to update your drawers with pieces that specifically focus on breathability and comfort while you're sleeping. But if you're often found breaking a sweat, switch it up to styles specifically created for sporting beneath activewear. (If you're looking for underwear that stands up to your sprints, check out the pair of high cut runner-specific undies, which give your legs plenty of running room, sans chafing). Even if your particular undies concern is more a question of "Is my panty line showing?" you better believe there's a style for that, too. They'll keep your outfit looking on point, and you'll no longer have panty lines poking through your tights- and leggings-heavy outfits. So without further ado, ahead are the four undies categories that could benefit from a little style update — and why.
It's no secret that undies can become not-so-pleasant after an active day of mowing the lawn or taking nieces and nephews to the park in the warm weather. This active thong has an antimicrobial treatment in the fabric that reduces odor and keeps you feeling great. Plus, the mesh fabric is breathable and quick drying to keep you cool. One user gives this panty five stars for being "the most comfortable thong she's ever worn."
Bustle may receive a portion of sales from products purchased from this article, which was created independently from Bustle's editorial and sales departments.
If you're a loungewear lover, it's time to update your drawers with pieces that specifically focus on breathability and comfort while you're sleeping. But if you're often found breaking a sweat, switch it up to styles specifically created for sporting beneath activewear. (If you're looking for underwear that stands up to your sprints, check out the pair of high cut runner-specific undies, which give your legs plenty of running room, sans chafing). Even if your particular undies concern is more a question of "Is my panty line showing?" you better believe there's a style for that, too. They'll keep your outfit looking on point, and you'll no longer have panty lines poking through your tights- and leggings-heavy outfits. So without further ado, ahead are the four undies categories that could benefit from a little style update — and why.
For Sleeping: Comfortable Undies in Breathable Fabrics
The experts at PopSugar suggest that "wearing tight underwear or a pair of polyester panties can lock in moisture and lead to yeast infections," so it's best to stick to cotton undies overnight while you sleep. Cotton allows for air circulation, which is important when you're sporting your undies for longer periods of time.Non-Binding Cotton Boyshorts
Hanes Invisible Premium Cotton-Blend Boyshorts (Sizes S-2X), $17-$29, Amazon
These cotton-blend boyshorts have a flexible elastic waist that won't dig in, as well as comfortable leg bands that make sure they won't ride up, causing you discomfort during the night. Bonus: These come in a pack of six with a variety of cute colors and prints — but you can pick your preference from six different pattern and style options.Ultra-Soft, Breathable Cheeksters With Cooling Technology
Adidas Women's Climacool Cheekster Underwear (Sizes XS-L), $10-$12, Amazon
When you sleep, you want a comfortable panty that has a full shape and an ultra-soft material that won't ride up while you snooze. The breathability in this lightweight Climacool underwear also helps you feel fresh when waking up, which might not happen if you're sporting constricting panties that retain heat. Bonus: This pair is tagless for added comfort. Plus, one user said that these cheeksters are so comfortable, you won't even notice you're wearing them.Waster-Resistant, Leak-Proof Undies
Leak Proof Control Briefs 3 Pack, $16, Amazon
Waking up to small leaks and stains on your clothes or sheets is the worst, so wearing leak-proof underwear to bed can help you sleep a lot sounder — knowing you've got everything in check. The lining in these comfort stretch panties is water resistant, keeping moisture from leaking into unwanted places, and they're breathable and hypoallergenic to keep your downstairs clean and irritation-free while you sleep. Plus, Joelle Barron, a contributor for Romper, tried leak-proof underwear for a week and "freaking loved them." Bonus: This set come in a pack of three cute colors and prints.For Working Out: Moisture-Wicking Fabrics That Don't Chafe
According to a study done on the subject, synthetic, sweat-wicking fabrics are better for keeping you comfortable while working out than their traditional cotton counterparts. The study said women were particularly receptive when it came to thermoregulatory benefits, so it's time to get serious about your undies set for sweating.Antimicrobial Sport Thong Fights Bacteria
ExOfficio Give-n-Go Sport Mesh Thong (Sizes XS-XL), $10-$22, AmazonIt's no secret that undies can become not-so-pleasant after an active day of mowing the lawn or taking nieces and nephews to the park in the warm weather. This active thong has an antimicrobial treatment in the fabric that reduces odor and keeps you feeling great. Plus, the mesh fabric is breathable and quick drying to keep you cool. One user gives this panty five stars for being "the most comfortable thong she's ever worn."
Breathable, Quick-Drying Brief
Champion Women's Absolute Brief (Sizes S-L), $7-$10, Amazon
Dr. Nicole E. Williams of the Gynecology Institute of Chicago told Elle.com to steer clear of sheer, lace, or silky underwear at the gym. She said, "when you exercise in non-breathable underwear like that, your vagina suffocates," which easily causes yeast infections. This machine-washable workout brief features Champion's unique vapor technology that evaporates moisture asap. With stay-put edges, they'll remain in place until the end of your workout class — and they're totally breathable with targeted ventilation (you can even snag the style in purple or pink, too!).Moisture-Wicking, Seamless Panty
Balanced Tech Seamless Bikini Panties 3 Pack (Sizes S-XL), $14, Amazon
Before you head to your next spinning class, make sure to have a selection of seamless underwear on deck. Sandra Lee, M.D., a board-certified dermatologist, told Womens Health, "if your underwear is old, the elastic becomes exposed and can potentially give you a rash." These three pairs of active underwear are anti-odor, breathable, and feature vital moisture control to keep you dry when working up a sweat. Bonus: These panties are machine washable, and you can choose your favorite three-pack from seven different color ways.High-Cut Running Underwear
ASICS Stride Brief (Sizes XXS-S), $24-$36, Amazon
For runners who are looking for underwear that gives them the most comfortable and simple leg movements, this workout panty with a high cut is made specifically for your strides. This pair also offers a soft fit and aerodynamic flat seam stitching. One user loves them so much, that she buys them for everyday wear.For Underneath Tight Clothes: No-Line Fabrics
When it comes to fighting a recurring VPL (visible panty line), there are plenty of nifty clothing hacks to employ. Cosmpolitan, for one, suggests sporting thicker fabrics on top, to minimize lines underneath. If you're not looking for a complete clothing overhaul though, it's worth it to check out the laser-cut fabrics and lacy alternatives to defined underwear lines.Silky, Invisible Laser Cut Panty
Calvin Klein Printed Invisibles Thong Panty (Sizes S-L), $9-$12, Amazon
This printed pair of silky panties are laser cut and barely there, so they're completely no-show under your tightest outfits. They're also tagless and lightweight, so you'll be both confident and comfortable in your hot new party dress. Bonus: These undies are machine washable, and you can pick your favorite pattern and color from four different options.No-VPL Lace Thong
Hanky Panky Original Thong (One Size, One Size Plus, One Size Fits Most), $20-$22, Amazon
A comfortable lace thong that promises no VPLs sounds too good to be true — but with this pair, you'll be wanting to wear a thong under everything. One size 18 reviewer said they love this pair, as it doesn't dig in at the wrong places or ride up after wearing them all day. Think wearing thongs is bad for your downstairs area? Dr. Jill M. Rabin, an Associate Professor of Women's Health told Huffington Post that unless you have a "predisposition to getting infections," there aren't "really any dangers" to wearing thongs.For Everyday Wear: Versatile, Multifunctional Styles & Fabrics
When it comes to finding the right undies for your everyday wear, think of the clothing styles and silhouettes you wear most often first. According to Alicia Vardo, an intimate apparel examiner, one of the most important areas to focus on is the crotch. She told Examiner.com, "The crotch of the panty should fit just right against your body. It shouldn't bunch up in the back or the front and should be snug." Think of the underwear styles that often get you this result, and go from there!Full Coverage, Mid-Rise Boyshorts
Victoria's Secret Everyday Boyshort Panty (Sizes M-L), $18, Amazon
These boyshort undies by Victoria's Secret were created with everyday wear in mind. They have a full coverage, mid-rise fit, and they're crafted from an ultra-smooth stretchy material. They'll look and feel good underneath your denim, dresses, or short shorts, and the back even features a cute ruche detail.Classic, Machine Washable Cotton Brief
Calvin Klein 3 Pack Radiant Cotton Bikini Panty (Sizes S-L), $25-$30, Amazon
A lingerie expert told Refinery29, “Briefs can be absolutely gorgeous and, unless you're trying to hide panty lines, are great for every day.” This three-pack of machine washable cotton briefs by Calvin Klein features the classic logo comfort waistband in a different variety of colors, plus a smooth fabric that's ready for all-day wear. One user gives this pair top ratings for being a high quality cotton panty that never causes wedgies (#important).Comfortable & Classic High-Waisted Panties
Bali Women's Cool Cotton Skamp (Sizes M-3XL), $4-$25, Amazon
If you prefer high-waisted fits to lower or mid-rise pants and denim (same here!), then it's time for you to snag yourself a pair of comfortable panties with a high waist. They'll make a world of difference and feel way more balanced underneath your favorite high-waisted shorts or skinnies. These ones have a tag-free design for added comfort, and the cool cotton fabric is breathable and moisture-wicking. One user bought this pair after her doctor recommended wearing cotton undies (because they're better for your v-region) and loves the fit, even under tightly fitting jeans.Bustle may receive a portion of sales from products purchased from this article, which was created independently from Bustle's editorial and sales departments.
Subscribe to:
Posts
(
Atom
)